Top ten at the midway point: Hinchcliffe, Power, Hunter-Reay, Castroneves, Briscoe, Andretti, Newgarden, Viso, Tagliani and Rahal.
Only two Hondas - Newgarden and Tagliani - are in the top nine in line for the pole shootout. In particular neither of the two main Ganassi drivers - Dixon and Franchitti - are looking likely to progress.
Update at 5.30pm BST (12.30pm Indiana time):
Tony Kanaan had the first qualifying run of the day and posted an average lap speed of 225.100s to set the first benchmark for Pole Day.
Simona de Silvestro missed her place in the pre-qualifying inspection line meaning that she could not take up her initial guaranteed qualifying run and will have to wait for everyone to complete their first run.
Katherine Legge also did not take up her spot, in what looked like a conscious decision by Dragon Racing to sit out the early sessions and possibly not make a qualifying run until Sunday's Bump Day.
Townsend Bell (221.514mph) and Scott Dixon (223.684mph) can't top Kanaan's time, but Will Power set a new provisional pole time of 225.339s. The fastest man in morning warm-up, Helio Castroneves, narrowly failed to beat that with a lap of 225.282s.
Andretti Autosport's first representative, Sebastian Saavedra, has a major engine failure on his run, but Ryan Hunter-Reay goes second with 225.289mph.
The two Dale Coyne Racing cars of Justin Wilson (222.929mph) and James Jakes (222.338mph) both struggle with handling; Wilson suggests that the wind might have picked up while Jakes speculates about climbing temperatures.
As if on cue, Bryan Clauson crashes shortly thereafter when he gets out of the groove into turn 2, spins and hits the SAFER barrier, demolishing the left rear of the car. He climbs out but looks shaken. There's a brief pause while debris is removed from underneath the SAFER barrier. Sarah Fisher Hartman Racing have a spare car, but it's in pieces according to team owner Sarah Fisher.
Dario Franchitti makes his run and posts a time of 223.582mph but says he's very unhappy with the car right now and that it seems the Honda cars don't have the speed. His Ganassi stablemates Graham Rahal post 223.868mph and 223.959mph respectively.