Andretti Autosport driver Justin Wilson has been airlifted to hospital after being involved in a serious accident near the end of Sunday's ABC Supply 500 at Pocono Raceway.

Wilson appeared to be struck in the head by flying debris after rookie driver Sage Karam spun out and suffered a hard hit against the wall at the tri-oval on lap 179 of 200.

A large piece of debris - which looked similar to a broken nose cone from the shattered #8 Ganassi car - appeared to fly into Wilson's cockpit as the Englishman navigated his way past the scene of the initial accident.

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Ambulance crews and safety workers were quickly in attendance. Karam was was helped from his car and appeared shaken and bruised, sitting on the side of his wrecked car until the ambulance arrived to take him to the in-field care centre where he was checked and send on to hospital by ground transport for further evaluation.

There was more immediate concern and attention paid to Wilson, with multiple crews attending the stricken Andretti car. Wilson was removed from the car and taken away by ambulance, and immediately airlifted away by the medical helicopter.

According to IndyCar sources, the former Formula 1 driver has been flown to Lehigh Valley Health Network Cedarcrest Hospital in Allentown, Pa., with an undisclosed head injury.

No further details have been given as to his condition on the nature of his injuries. His team boss Michael Andretti had no additional information on the 37-year-old's condition.

The race eventually finished under yellow, and Wilson's team mate Ryan Hunter-Reay picked up his second win of the season. However, Hunter-Reay's first conversations when he arrived in victory circle were about his team mate, and celebrations were muted as the paddock awaited word of Wilson's status.

Further updates to this story will be made in due course as and when available.