The clean-up from Jakes' accident took nine laps and racing resumed on lap 32, with Franchitti once again leaping away into the lead ahead of the KV duo, then followed by Helio Castroneves, Oriol Servia and Ryan Briscoe who all got ahead of Danica Patrick who was not having the best of days at restarts. She was also passed on track for seventh by her team mate Marco Andretti, who was already up ten places from his qualifying position and looking particularly strong in the night conditions.
The green flag was fairly short-lived, with another accident on lap 45 bringing out the second caution of the evening. Ana Beatriz had got loose on the same unsettling Iowa turn 2 bump and gone flying up the track, only this time she picked up some company along the way and smashed hapless Mike Conway into the wall as she went. Both cars were badly damaged and showered debris over the track, with Vitor Meira one of the first to arrive at the accident scene to find himself getting a face full of a sheet of carbon fibre bodywork that damaged his car, ultimately causing the team to retire the #59 with handling problems late in the event.
"We got loose, I hit the bump and the rear snapped on me," said Beatriz succinctly.
Conway had more to say: "It was obviously a disappointing end. I was just following Ana into turn 1 and 2, and she just got loose in the corner. I had nowhere to go and we kind of touched wheels," he explained. "That set me off into the wall. It was a pretty hard hit; not much left of the right side of the car ... It was a funny day anyway. At the start we had no gears and we drove right to the back. It's unfortunate, but that's the way it goes sometimes."
It was a lengthy 19-lap delay to clear up the debris and fluids spilt from the two wrecked cars before racing resumed on lap 63 with another great restart from Dario, while Helio Castroneves suddenly surged past the KV duo to claim second spot; Kanaan had problems trying - and finally failing - to keep third place from an assertive Marco Andretti in the Venom #26 car, while further back Ryan Briscoe and JR Hildebrand went side-by-side and touched wheels as they scrapped over sixth place.
With Kanaan admitting over the team radio that he had "no answer" for Dario and no idea where to look for one, it seemed that the prospects for a real battle for the lead lay with Castroneves - ironically, given the off-track spat between Helio and Dario over blocking following the Milwaukee 225 last weekend. But just when it seemed as though we were in for a rematch, we got deja vu instead: just like at Milwaukee, Helio suddenly had a tyre go down and he had to take to the pits for a green flag pit stop on lap 77, which put him a lap down and essentially stopped him playing any further role in the fight for the win.
Worse news was to follow for Team Penske, when the rear end of Will Power's #12 suddenly snapped round on him over the turn 2 bumps and sent him into a nasty hit against the wall. "That hurt," he admitted afterwards, and he looked visibly shaken and dazed even half an hour later when he stepped out of the in-field care center.
Although he initially asserted that he was fine and there was no concussion, official word said otherwise and he was deemed to have suffered a minor concussion that means he will need to undergo medical re-evaluation tests before being cleared to race at the next event in Toronto in two weeks time, as will Simona de Silvestro who was ruled out of Iowa after failing the same tests ahead of Friday practice after suffering post-concussion symptoms from a crash at Milwaukee.
"It was definitely a hard hit," admitted Power, who said that it definitely "rang my bell". He went on: "The Verizon car was damaged after the incident in the pits and we just had a problem with the steering and it came around on me. It's a tough result for us tonight. We'll do our best to get it back next race."
He also lamented the fact that the problem had originated with a mistake by the team in the pits. "Once again we screwed ourselves in the pits, like we always do," he said, insisting that the team had to learn from this and cut out these costly missteps.
The caution allowed everyone to pit, and JR Hildebrand had an eventful time when he was caught out by the car of Marco Andretti in front and nearly made contact, avoiding it only with a major swerve that had the pit crews still working on the business side of the pit wall flinching. Hildebrand then caught out again and almost ran into the back of Scott Dixon behind the safety car as everyone was weaving and testing their brakes to heat up their equipment ahead of the restart on lap 106.