Dovizioso lost out on a first podium finish of the season by just 0.562sec to team-mate Dani Pedrosa last time out at Le Mans and finished eighth at last year's Italian Grand Prix.
"I really look forward to the GP of Italy. Mugello is a unique place in terms of atmosphere and, although it's part of the world championship, for me it's an event that stands alone,” he said. “It's like a kind of ritual with so many memories from previous years: Tuscany, the colours and smell, the people, the food and the passion of the fans.
“Although I'm Italian I don't actually ride much at this track because we don't test here, so we come back after a full year away. We know the key places where we have to get the set-up right but it always takes a while to master the track again. There are a lot of fast changes of direction and that means riding here requires a lot of physical energy. It's bumpy too which complicates things further.
“As an Italian rider, the support of the fans gives me an extra drive, and the hour before the race is really special. It's important to use that boost to lift your performance and that's what I'll be aiming to do on Sunday."
The #4 will start his home event joint fifth in the championship with Marco Melandri and 14 points behind the top Honda of Pedrosa.