The inclusion of the new Silverstone 200 support races at this weekend's British MotoGP has provided the rare chance to compare the performance of a front-running BSB bike with the grand prix machines.
The open-class Silverstone 200 has attracted entries from BSB, WSS, BSS and BSTK.
Friday's single free practice session saw the Rapid Solicitors BSB Kawasaki ZX-10Rs of Byrne and team-mate Stuart Easton leading the way.
Riding after the two MotoGP practice sessions (one wet and one dry) had finished, 2012 BSB race winner Byrne set a best time of 2m 10.186s during his ten Friday laps.
That was 1.7s clear of nearest rival Easton and quicker than three CRT MotoGP riders.
Byrne's time was also just a fraction off fellow PBM rider James Ellison's best practice time on the Aprilia CRT, although the changeable weather meant the leading MotoGP lap times were over a second from the 2010 800cc race lap record.
It is assumed that the PBM Kawasakis are in their normal BSB spec, which includes a control ECU banning electronic rider aids such as traction and wheelie control. Byrne said he had been using "some worn [Pirelli] tyres from Snetterton".
The '200 entry list also allows a comparison between WSS and Moto2, with PTR-Honda's Jules Cluzel setting the third best time in '200 free practice courtesy of a 2m 12.059s best. Team-mate and fellow 2012 WSS race winner Sam Lowes was a fraction slower.
Cluzel's time is some way off the fastest Moto2 Friday lap of 2m 8.826s by Pons Kalex rider Pol Espargaro, which would have put the Spaniard 14th on the MotoGP timesheets.
Qualifying for the Silverstone 200 will be held at midday on Saturday. The two 16 lap races then take place following the MotoGP qualifying session on Saturday and after the MotoGP race on Sunday.