World championship leader Jorge Lorenzo, who starts this weekend with a 13-point advantage over Repsol Honda's Dani Pedrosa, spent part of the session chatting with Giacomo Agostini and Phil Read in the Factory Yamaha pits.
Lorenzo and Pedrosa never looked like taking to the track today, meaning - like their rivals - they will have to cram in their usual preparation into the three track sessions that remain prior to Sunday's grand prix.
Local hero Valentino Rossi, making his final home appearance as a Ducati rider, took to the track at the midway stage of the afternoon, but rain spots sent him back into the pits without crossing the finish line.
Rossi has a new chassis and swingarm to try this weekend.
Fortunately, the Misano weather is forecast to improve as the weekend goes on.
Rea is riding with the #56 this weekend, his usually #65 in WSBK having been retired by MotoGP after Loris Capirossi's final race.
Friday practice (2):
1. Karel Abraham
2. James Ellison
3. Michele Pirro
4. Yonny Hernandez
5. Jonathan Rea
6. Danilo Petrucci
7. David Salom
8. Ben Spies
9. Randy De Puniet
10. Mattia Pasini
11. Alvaro Bautista