"In 2013 our job will be to provide him with well organised teamwork and a competitive bike that will give him the confidence to produce that kind of ride in many races, not just one."
The date for McPhee's FTR Honda debut is not yet known, but he will complete his 2012 racing activities in a week's time when he returns to Valencia for the final round of Dorna's CEV Buckler series. He is currently fifth in the standings.
The race will be his final competitive ride with the RSF-backed KRP squad with which he has raced in the 125GP and Moto3 classes in the UK and Spain since 2010.
RSF founder Graham Sharp said the step up to a full season's ride in the World Championship was a natural career progression for McPhee.
"When we decided to add motorcycle racing to our remit at the end of 2009 we said our number one objective was to progress a British rider all the way through to MotoGP and this is a significant step towards that goal.
"Our first move was to forge an alliance with Mark Keen's KRP team which has done a fantastic job in developing John as a rider to the point where he can now hold his own at Grand Prix level.
"Mark and the team will continue to bring on our other riders in the CEV Moto3 series in Spain but the time is right for KRP to hand over the baton to RTG for the next chapter of John's career.
"If everything goes to plan, I'm certain John and the team will produce some respectable results together. RTG is a strong and well-respected squad which, with former 250cc GP rider Dirk Heidolf at the helm, knows how to develop young riders as well as run a Grand Prix team."
McPhee's best finish so far this year is a 15th place at Brno.