“It's a 'Micky Mouse' track that's small for MotoGP and therefore difficult and tricky. There are a bunch of left hand corners, and I normally prefer those that go to the right.
“Anyway, we'll see. The asphalt was redone and that should have improved both the grip and the bumps.
“It will be a strange weekend that should be challenging for a few different reasons, but we'll do our best.”
Team manager Vittoriano Guareschi added: “It's the last race, and we have the chance for Valentino to finish the season in fifth place. We'll all do our best to help him achieve that.”
Team-mate Nicky Hayden has been the only other Ducati rider to finish on the podium during the Rossi-era, courtesy of a damp race at Jerez 2011.
Rossi, a winner of 79 races for Honda and Yamaha, is returning to Yamaha next season, where he will re-join double world champion Jorge Lorenzo at the Factory M1 team.
Rossi will make his 1000cc Yamaha debut in the post-race test on Tuesday and Wednesday, when his replacement Andrea Dovizioso will complete his first Desmosedici laps.