Having finished no further than 4.1s from victorious team-mate Marc Marquez in the previous five events this year, Dani Pedrosa was left 14 seconds adrift at Mugello.

Pedrosa had qualified a close fourth despite an engine mapping mishap, but dropped to eighth on the opening lap of the race.

The Repsol Honda rider finally got the better of Ducati's Andrea Iannone to reclaim fourth on lap 10 of 23, where he remained to the chequered flag. The result means Pedrosa has lost second in the world championship to Valentino Rossi.

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The Spaniard, who underwent arm pump surgery between the Jerez and Le Mans rounds, said:

"I had a nice battle with Iannone. We were fighting a lot. Unfortunately my arm is still causing me issues. The arm is swollen and not recovering as fast as I thought. Anyway the team understands the situation, which I appreciate.

"Tomorrow I will go for a check-up with Dr. Mir and hope to be fitter in time for Montmelo in two weeks time."

Fitness aside, Pedrosa's biggest concern was that he only set the fifth fastest lap of the race, 0.569s slower than Marquez.

"I was not fast enough today," he declared. "At Le Mans my fastest race lap was close to the top, also in Jerez and Argentina, but here I was not even close to the fastest time. So we are missing a little pace in the race."

Pedrosa now aims to regroup ahead of what he hopes will be a home victory battle with Marquez and Lorenzo in Catalunya.

"I just watched the last laps from Marc and Jorge and it looks so fun. Very exciting. I hope in Barcelona to get more energy with the arm and to be there with them to battle for victory," he said.

"At the moment the only guy who is really consistent is Marc, he is riding superb and not making mistakes this time. Of course he is doing very well.

"My target is to be faster, closer and to do a good race from beginning to end. Today Jorge put a good fight to Marc, but Marc was able to do a strong finish."