The factory KTM team will make its much-anticipated MotoGP debut as a wild-card entry for test rider Mika Kallio at the Valencia season finale.
Kallio has not raced since last year's Valencia Moto2 round, while the RC16 has completed 35 days of track testing ahead of this weekend's race.
“The start in Valencia will be a remarkable moment," Kallio said. "KTM is presenting this new bike, and it is a great honour to be the one to compete with it for the very first time.
"This whole year has been great, and I couldn't imagine a better way to end the season. This coming weekend will be memorable for me, and for all the KTM staff. The team will have valuable experience working under pressure, and I can finally enjoy riding MotoGP again.
"I'm not going to be at the back of the pack in this race. I'll be focusing on some of my personal goals after the timed free practices. I can race without pressure, and I believe I'll be on fire when the lights go out."
Kallio will then hand over to 2017 race riders Bradley Smith and Pol Espargaro for next week's post-race test.