At this point teams were looking ahead to the end game and feverishly calculating fuel loads and possible tyre strategies: Dale Earnhardt Jr. had been religiously taking four new tyres at every pit stop so far while Juan Montoya's #42 team were planning on two tyres only from here on, Busch's #22 team were planning fuel strategies to see off the #99 of Edwards, while Jimmie Johnson and Jeff Gordon were now running 6th and 7th after their earlier problems although somewhat off-sync in terms of stops. But Tony Stewart was looking particularly strong, having found the best compromise between handling through the corner apex (albeit describing the #14 as a little tight) versus getting out of the corner cleanly and allowing him to put the power down early giving him maximum speed and chances for overtaking traffic.
A debris caution on lap 214 allowed everyone the opportunity to pit under yellow, with a wide variety of strategies emerging including Joey Logano opting to stay out altogether and assume the lead and Clint Bowyer gaining ten spots with a fuel-only approach. Jimmie Johnson must have wished he could have gone fuel-only too when his own pit stop ended up with a missing lugnut, an irritatingly frequent recurring theme for the #48 over the past year which meant he had to return to pit lane and fall to the back of the lead lap.
At the restart, Marcos Ambrose surged past Logano to lead lap 222 with Montoya looking strong behind them, but Brian Vickers' strong day was about to come to a premature end when he spun on the front straight and hit the wall on lap 225. Vickers headed to the garage for lengthy repairs, Logano finally headed in for fuel, Mark Martin got the free pass and Clint Bowyer assumed the lead followed by Ryan Newman and Jeff Burton.
Bowyer's old tyres were no match for Newman's fresh ones and the polesitter duly reassumed the lead, with Greg Biffle moving past Bowyer into second place. At this point the critical factor was emerging as fuel, with Biffle being told he was eight laps short of going full distance and Kurt Busch in fourth similarly advised he was five laps shy of making it to the chequered flag.
If it was a caution they needed then Jimmie Johnson duly obliged by spinning on turn 2 on lap 240 after contact with Juan Montoya, bringing out the tenth (and ultimately final) yellow of the afternoon. "We had some issues on pit road," said Johnson, "And then the #42 - I don't think of the three times he's wrecked me it's been intentional, but he's out of mulligans and I've had enough of, 'Oh, I'm sorry, and you're spun out.' It's happened way to often."
Greg Biffle decided there was no chance of being able to make it all the way to the end without a further stop and duly came in, as did Dale Earnhardt Jr. who had been suffering a suspected tyre rub on his left front; unfortunately he then picked up a tyre violation that put him to the back of the leap lap in 33rd. Earnhardt had already been unhappy with the change of tyre compounds this weekend, which Tony Stewart had earlier praised as being "grippier" and the key to his team's qualifying success but which met with less success on the #88.
"We struggled all weekend," admitted Earnhardt. "In practice we just didn't really have the speed we had last year. We've just got to figure out why. What's the difference in this tyre and try to figure it out. I mean, every damn week they change the tyre ... I guess [NASCAR] is getting on 'em about how they build them or something, and they had to bring a new one here. Some kind of new construction. I didn't like it."
Stewart-Haas had learned from last year's autumn race at New Hampshire and knew that track position was crucial at this point of proceedings, so Newman stayed out in the lead ahead of Kurt Busch, Carl Edwards and Denny Hamlin as the race resumed on lap 245 with 56 laps to go to the chequered. Busch was looking strong going into the corners, but critically Newman was faster out of them which allowed him to get the power down and pull away out of trouble to keep the lead.
The focus from this point was on the continuing surge of Jeff Gordon who was back up to fourth, and a strong recovery by Jimmie Johnson after the lugnut and spin problems. There was also the relentless rise of Tony Stewart, back into the top ten after the restart and passing Carl Edwards (who had dropped back to fifth) 20 laps later.
Most people however were having to run with one eye on the fuel gauge: Regan Smith, Jamie McMurray and Juan Montoya were all among those to run dry before the end. A rare exception was Newman himself who didn't seem to be sparing the horsepower as he pulled out a lead of nearly 2s over Kurt Busch before the #22 was forced to give up the chase and fell to fifth in extreme fuel conservation mode - he would eventually run dry on the last lap and finish in tenth. That allowed Tony Stewart up another place, then past Gordon on lap 286 and finally swooping on Denny Hamlin for second place on lap 294. In the remaining seven laps Stewart put his foot down and did everything he could to close on his team mate who was now encountering lapped traffic and worrying about his fuel load, which allowed the #14 to cut the lead back to under a second.