Further back, some of the star performers from race one, Shane Byrne, Broc Parkes and Jamie Hacking, were having a tougher time. Byrne was running well in the early stages but would drop to the back of the field on lap five, while both Kawasaki riders found themselves outside the top twenty at the end of the opening lap. Worse was to follow for Hacking when he clipped the back of Luca Scassa's Pedercini ZX-10R, sending the Italian skyward and out of the race, while the American was delayed to the back of the field.
Back at the front, Haga's attempt at a podium finish began to falter as the race reached its midway point having fallen away from Rea and Haga, while Kiyonari, a charging Leon Haslam, Jakub Smrz and Shinya Nakano would also find their way through eventually.
Of those getting backed up behind Rea, Haslam was making the most prolific progress, forcing Kiyonari to sit up as he dived through to assume fourth position.
Indeed, the Stiggy Honda rider looked the most likely candidate to wrestle third from Rea's grasp, which he did momentarily on lap 17, only for the Ten Kate machine to slip back through at the start of lap 18.
However, just as Haslam was gearing up for a last lap challenge to secure third podium of the season for himself, he lost the front end of his machine on the run up to Attitude, putting him out of the race, much to his obvious disappointment.
At the same time, Spies was crossing the line to celebrate his second win of the day, five seconds up on Fabrizio after the Italian's spirited mid-race assault, in which he kept the gap to his rival pegged at less than two seconds, faltered towards the end.
Haslam's demise meant Rea was fairly comfortable as he crossed the line for his second podium in consecutive events, while the outcome also sees him overtake Haslam for fourth in the overall standings. He finished ahead of Biaggi and Kiyonari, who were also to capitalise from the Briton's error to secure top five results.
Smrz completed a decent weekend for himself in sixth, ahead of Nakano – bandaged up after his race one accident – and Haga, the championship leader having his first 'off' weekend this season as he fell away substantially from the fight ahead of him.
Tom Sykes kept his finishes ticking over in ninth, up from 21st on the grid, ahead of Byrne, whose charge back through the field would most likely have seen him fighting for the podium had it not been for his earlier delay. The same could be said for Parkes, who scythed his way past a number of rivals to finish 11th.
A forgettable weekend for Suzuki ended with Yukio Kagayama
and Fonsi Nieto
finishing line astern in 12th and 13th, ahead of series returnee Lorenzo Lanzi, while Haslam's late retirement would actually promote his Stiggy team-mate Jake Zemke up to 15th to score his first WSBK point.