Cal Crutchlow began the race from 20th and last after missing Saturday's qualifying session due to an ankle injury.

Teammate Andrea Dovizioso fell and rejoined.

Cardion AB Ducati's Karel Abraham was absent this weekend due to finger fractures in his left hand sustained during testing at Aragon.

Silverstone was the first event where the new specification front slick tyre becomes standard.

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1. Jorge Lorenzo ESP Yamaha Factory Racing (YZR-M1) 41m 16.429s
2. Casey Stoner AUS Repsol Honda (RC213V) 41m 19.742s
3. Dani Pedrosa ESP Repsol Honda (RC213V) 41m 20.028s
4. Alvaro Bautista ESP San Carlo Honda Gresini (RC213V) 41m 21.625s
5. Ben Spies USA Yamaha Factory Racing (YZR-M1) 41m 27.960s
6. Cal Crutchlow GBR Monster Yamaha Tech3 (YZR-M1) 41m 31.541s
7. Nicky Hayden USA Ducati Team (GP12) 41m 31.956s
8. Stefan Bradl GER LCR Honda MotoGP (RC213V) 41m 38.950s
9. Valentino Rossi ITA Ducati Team (GP12) 41m 52.567s
10. Hector Barbera ESP Pramac Racing (GP12) 41m 57.757s
11. Aleix Espargaro ESP Power Electronics Aspar (ART CRT) 42m 19.586s
12. Randy De Puniet FRA Power Electronics Aspar (ART CRT) 42m 19.872s
13. Michele Pirro ITA San Carlo Honda Gresini (FTR-Honda CRT) 42m 23.719s
14. James Ellison GBR Paul Bird Motorsport (ART CRT) 42m 31.211s
15. Yonny Hernandez COL Avintia Blusens (FTR-Kawasaki CRT) 42m 31.537s
16. Colin Edwards USA NGM Forward Racing (Suter-BMW CRT) 42m 46.328s
17. Danilo Petrucci ITA Came IodaRacing (Ioda-Aprilia CRT) 42m 56.731s
18. Ivan Silva ESP Avintia Blusens (FTR-Kawasaki CRT) 43m 8.528s
19. Andrea Dovizioso ITA Monster Yamaha Tech3 (YZR-M1) +1 lap

DNF: Mattia Pasini ITA Speed Master (ART CRT)