Jorge Lorenzo bolted clear for his fifth victory of the year in Sunday's San Marino MotoGP, at Misano.

Pole sitter Marc Marquez dropped to a low of fourth after an early braking mistake, then repassed Valentino Rossi and Dani Pedrosa.

Rossi dropped away from the Hondas in the second half, while Pedrosa and Marquez exchanged second place several times.

Marquez confirmed the runner-up spot in the closing laps, finishing 3.4s from Lorenzo, meaning Marquez's title lead has still grown from 30 to 34 points - but with Lorenzo and Pedrosa now tied for second.

Lorenzo and Rossi were using the factory's new seamless shift gearbox for the first time in a grand prix.

Aleix Espargaro, who had qualified on the second row, received a jump start penalty.

Ducati test rider Michele Pirro was again replacing the injured Ben Spies at Pramac.

CLICK HERE for pictures from the grand prix...

1. Jorge Lorenzo ESP Yamaha Factory Racing (YZR-M1) 44m 5.522s
2. Marc Marquez ESP Repsol Honda Team (RC213V) 44m 8.901s
3. Dani Pedrosa ESP Repsol Honda Team (RC213V) 44m 12.890s
4. Valentino Rossi ITA Yamaha Factory Racing (YZR-M1) 44m 20.584s
5. Stefan Bradl GER LCR Honda MotoGP (RC213V) 44m 27.877s
6. Cal Crutchlow GBR Monster Yamaha Tech 3 (YZR-M1) 44m 28.121s
7. Alvaro Bautista ESP Go&Fun Honda Gresini (RC213V) 44m 36.581s
8. Andrea Dovizioso ITA Ducati Team (GP13) 44m 48.224s
9. Nicky Hayden USA Ducati Team (GP13) 44m 50.380s
10. Michele Pirro ITA Ignite Pramac Racing (GP13) 44m 53.340s
11. Bradley Smith GBR Monster Yamaha Tech 3 (YZR-M1) 44m 53.533s
12. Colin Edwards USA NGM Forward Racing (FTR-Kawasaki CRT)* 45m 8.676s
13. Aleix Espargaro ESP Power Electronics Aspar (ART CRT) 45m 13.122s
14. Hiroshi Aoyama JPN Avintia Blusens (FTR-Kawasaki CRT)* 45m 21.050s
15. Danilo Petrucci ITA Came IodaRacing Project (Suter-BMW CRT)* 45m 23.429s
16. Claudio Corti ITA NGM Forward Racing (FTR-Kawasaki CRT)* 45m 35.177s
17. Randy De Puniet FRA Power Electronics Aspar (ART CRT) 45m 39.512s
18. Michael Laverty GBR Paul Bird Motorsport (PBM-ART CRT)* 45m 42.382s

Bryan Staring AUS Go&Fun Honda Gresini (FTR-Honda CRT) DNF
Hector Barbera ESP Avintia Blusens (FTR-Kawasaki CRT)* DNF
Yonny Hernandez COL Paul Bird Motorsport (ART CRT) DNF
Karel Abraham CZE Cardion AB Motoracing (ART CRT) DNF
Andrea Iannone ITA Energy T.I. Pramac Racing (GP13) DNF
Lukas Pesek CZE Came IodaRacing Project (Suter-BMW CRT)* DNF

* Standard ECU.

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