Improvement from Bastianini, but he only goes up to 11th and is still 0.885s off the pace.
New soft front tyre but the same medium rear he started the session with on run 2 for Alex Marquez, and he goes fastest on a 1:31.600.
More updates for Honda this year after the new chassis, a new exhaust is on both of Marini's and both of Mir's bikes for this session, as reported by MotoGP.com.
Pedro Acosta the top-KTM at the minute but he's down in ninth at the moment. Looked to be improving on his last lap but it went away in the last split.
Not a great couple of minutes for Yamaha.
Fernandez has stopped on-track aboard the V4.
Oliveira then crashed at the final corner. His bike reached the fence but he seems to be okay.
Marc Marquez back out on the same tyres he started the session with and he's fone to the top on a 1:31.627.
Difficult start for last year's Emilia-Romagna winner Enea Bastianini, down in 17th. His split with crew chief Alberto Giribuola has been well documented since Barcelona.
Bastianini is now working with Xavi Palacin.
Morbidelli into the top-10 with his latest lap, P6 for the Italian who of course is a bit delayed in this session after his 10-minute suspension.
Mir looked on for a top-10 lap there but he got held up with Chantra in the last turn.
Most riders heading back to the pits now, actually.
Early top-10:
Bezzecchi
Di Giannantonio
Marini
Quartararo
M. Marquez
Bagnaia
A. Marquez
Acosta
Vinales
Martin
Marc Marquez back in the box. P5 after his first run and all of 0.117s off the top.
Di Giannantonio moves up to second with a 1:31.794, Bezzecchi back to the top on a 31.764.
Marini now fastest on a 1:31.866, 0.009s between him and Quartararo at the top.
Bezzecchi briefly took over at the top but Quartararo back to P1 now with a 1:31.875.
However this weekend ends up for Fernandez and the V4, it is good to see a factory Yamaha in blue.
Di Giannantonio takes over at the top, but he's quickly displaced by Quartararo on a 1:32.083. 0.327s advantage for Quartararo.
Early benchmark from Marc Marquez at a 1:32.496, 0.416s clear of Bagnaia.
Fabio Quartararo running another new number design that you can't read. Probably looks very nice up-close.
Pit lane is now open in Misano and we are underway for FP1 in San Marino.
Franco Morbidelli will not be riding in the first 10 minutes of FP1 for disobeying marshals' instructions after he crashed out of the Catalan GP last Sunday.
Fabio Quartararo, as ever, will be Yamaha's best hope of a result this weekend, and he himself has good memories of this Misano World Circuit Marco Simoncelli, having wrapped up the 2021 world title here four years ago.
But the main attention around the Iwata marque this weekend will be around Augusto Fernandez, who will be racing Yamaha's V4 engine.
Quartararo tested it for the first time at Barcelona earlier this week, on Monday, but this will be the first time the engine has been used on a race weekend or in a public scenario.
For Marc Marquez, his brother's win in Barcelona means there's no chance for him to wrap up the title in Misano this weekend.
He is 182 points clear, though, so little need to worry at this stage for him about getting it wrapped up at some point in the Asian tour that will begin after this weekend.
A five-time winner at Misano, Marquez also won here in last year's first Misano race which was rain-affected.
Alex Marquez has a best finish in MotoGP of only fifth at Misano, but comes here on the back of a second career win, and second win of the season, last weekend in Misano.
Conditions are pretty ideal in Misano ahead of this FP1 session that is just 10 minutes away.
We're looking at 26C air temperature and 28C track temperature at the moment, although expect both, especially track temperature, to climb as the session progresses.
Welcome to live coverage of today's practice sessions from the San Marino MotoGP at Misano.
There's currently just a couple of minutes remaining in Moto2's opening session of the weekend, and MotoGP FP1 is due to start in around 15 minutes at 10:45 local time.