The 2025 Italian MotoGP is set to get underway at 14:00 local time, 13:00 BST.
Marc Marquez starts from pole position after securing his 100th pole in Q2 yesterday. The Spaniard, whose only premier class win at Mugello came back in 2014, but he was victorious in yesterday's Sprint by a comfortable 1.4 seconds.
Alex Marquez was secure in second place yesterday, ahead of Francesco Bagnaia in third. They start in the inverse of that order today, Bagnaia having managed his best qualifying result of the season yesterday with second place. The Italian is also the victor of the past three grands prix at Mugello.
Maverick Vinales starts from the middle of row two but showed decent speed yesterday and could be in podium contention today.
Fabio Quartararo will be hoping for an improvement in tyre life and rear chatter compared to the Sprint, where he slumped to 10th place.
Fabio Di Giannantonio was also a potential podium contender yesterday without losing positions at the start, but he will have to come from row three to secure a first premier class home podium today.
It's victory for Marc Marquez in Mugello. A 93rd for the Spanish rider, who is now 40 points clear at the top of the World Championship.
Alex Marquez holds off a charging Di Giannantonio for second, Bagnaia 2s adrift of the podium in the end - that feels colossal for the two-time champion.
Bezzecchi the best non-Ducati in fifth, ahead of Morbidelli who takes sixth after his LLP.
Di Giannantonio up to third with a beautiful move at turns six and seven. Bagnaia off the podium, and already out of contention after only a couple of corners.
Two to go now in Mugello but Bagnaia would wish that were one less. Di Giannantonio absolutely all over him for third place and just looks faster everywhere.
Tough to see where he might be able to pass, though.
Di Giannantonio continues to pressure Bagnaia but he's not made a move yet as we move to three laps to go.
Feels like if he does make a move he'll be able to hang onto it.
Over two seconds now for Marquez.
Better lap for Di Giannantonio that time and he's within a couple of tenths of Bagnaia now.
Almost 1.7s now for Marquez at the front.
Alex Marquez has 0.6s over Bagnaia, who has 0.4s over Di Giannantonio who seems to have stalled a bit since he got into Bagnaia's dirty air.
Marquez has this race sewn up, and Bagnaia is now very much more in a battle for third than for second.
1.1s between the Marquezes, Bagnaia now 0.8s behind the second of those, and Di Giannantonio now within half-a-second of Bagnaia who is in real danger of losing a podium spot here.
Still a second between the Marquezes, Marc back into the 1:46s that time and Alex down to a 1:47.1. Bagnaia 0.2s slower again, but he still has 0.9s over Di Giannantonio.
Rather feels like it's devolving into front tyre management.
Marquez a couple of tenths faster than Bagnaia that time, Di Giannantonio closing on his compatriot as well.
At the front, Marc Marquez's lead is over a second.
Marquez had over a second briefly on lap 12, but it's dropped back under again over the line. Bagnaia now back to the rear tyre of Alex Marquez.
Morbidelli has re-taken his LLP but made it cleanly this time. He's back to seventh now, behind Bezzecchi and Raul Fernandez, and ahead of Acosta.
0.5s between the leading two, Bagnaia a further 0.6s off Alex Marquez.
Jack Miller has entered the pits.
Morbidelli took his LLP on lap 10, but he went wide and outside the white lines, so he'll have to do it again.
10 laps in now, and it's still Marc Marquez who leads. Alex Marquez just about hanging on in second and Bagnaia isn't completely done yet within 0.7s of the lead.
Morbidelli has been handed a long lap penalty for the Vinales incident, and he's been passed by Di Giannantonio for fourth, as well.
Clear contact between Morbidelli and Vinales that led to the KTM rider's crash. Feels like a penalty might be on the way for the Italian there.
Vinales has crashed out at turn five. He's pointing to his head which would indicate he might not feel it's his fault.
Better lap for Bagnaia that time but now it's Marc Marquez to the front at turn one.
Vinales through on Morbidelli for fourth, too, as we start lap nine.
0.5s for Alex Marquez entering the final corner that time but Marc to within 0.2s with the slipstream on the straight.
Bagnaia still third but he's dropping off.
Morbidelli, Vinales, Di Giannantonio not far behind, either.
Some lap that from Alex Marquez. Immediately into the 1:46s for the first time and that's stretched them out a bit.
Marc Marquez up to second at turn one of lap seven, Bagnaia back to third.
Bagnaia wide exiting the final corner and Marc Marquez leads over the line.
Bagnaia back to the front at turn one and Alex up to second.
Now Alex leads at turn three.
Johann Zarco has crashed in sector four.
