Marquez wins the French MotoGP at Le Mans, Honda's 300th premier-class victory, after fending off an early Ducati challenge.

Miller - who briefly passed Marquez to lead - later lost out to factory team riders Dovizioso and Petrucci, Petrucci claiming his first podium since the same event last year.

After initially mixing it with the leaders, Rossi settled into fifth before closing on Miller at the end of the race.

KTM's Espargaro delivered the best dry performance for the RC16, during the race debut for the factory's carbon-fibre swingarm.

Vinales was taken out by Bagnaia, while home star Quartararo had a poor first lap before an impressive recovery from 16th.

Aprilia's Espargaro received a 1.4s post-race penalty for cutting the track.

Abraham and Mir fell in separate incidents on the warm-up lap. Abraham was later black-flagged for leaving pit lane after the leader crossed the finish line at the end of the first lap.

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  1. Marc Marquez ESP Repsol Honda (RC213V) 41m 53.647s
  2. Andrea Dovizioso ITA Ducati Team (GP19) 41m 55.631s
  3. Danilo Petrucci ITA Ducati Team (GP19) 41m 55.789s
  4. Jack Miller AUS Pramac Ducati (GP19) 41m 56.587s
  5. Valentino Rossi ITA Monster Yamaha (YZR-M1) 41m 56.700s
  6. Pol Espargaro ESP Red Bull KTM Factory (RC16) 41m 59.582s
  7. Franco Morbidelli ITA Petronas Yamaha SRT (YZR-M1) 42m 0.834s
  8. Fabio Quartararo FRA Petronas Yamaha SRT (YZR-M1)* 42m 2.086s
  9. Cal Crutchlow GBR LCR Honda (RC213V) 42m 3.500s
  10. Alex Rins ESP Suzuki Ecstar (GSX-RR) 42m 7.356s
  11. Jorge Lorenzo ESP Repsol Honda (RC213V) 42m 8.650s
  12. Aleix Espargaro ESP Factory Aprilia Gresini (RS-GP) 42m 23.159s
  13. Johann Zarco FRA Red Bull KTM Factory (RC16) 42m 26.708s
  14. Hafizh Syahrin MAL Red Bull KTM Tech3 (RC16) 42m 29.128s
  15. Miguel Oliveira POR Red Bull KTM Tech3 (RC16)* 42m 29.691s
  16. Joan Mir SPA Suzuki Ecstar (GSX-RR)* +1 lap
    Takaaki Nakagami JPN LCR Honda (RC213V) DNF
    Andrea Iannone ITA Factory Aprilia Gresini (RS-GP) DNF
    Maverick Viñales ESP Monster Yamaha (YZR-M1) DNF
    Francesco Bagnaia ITA Pramac Ducati (GP18)* DNF
    Tito Rabat ESP Reale Avintia Ducati (GP18) DNF
    Karel Abraham CZE Reale Avintia Ducati (GP18) DNF

* Rookie.

By Peter McLaren